Sometimes i find the Trend Micro OfficeScan is annoying when u wanna download some stuff from some cracks sites..so to disable the real time scan using command prompt, you can follow this guide..
1. Start command prompt. Start->run-> cmd
2. Type "net stop tmlisten"
3. Type "net stop ntrtscan"
and voila you Trend Micro OfficeScan real time scan is disable!!